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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZAP70
All Species:
15.15
Human Site:
S166
Identified Species:
30.3
UniProt:
P43403
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43403
NP_001070.2
619
69872
S166
E
R
M
P
W
Y
H
S
S
L
T
R
E
E
A
Chimpanzee
Pan troglodytes
XP_515637
619
69840
S166
E
R
M
P
W
Y
H
S
S
L
T
R
E
E
A
Rhesus Macaque
Macaca mulatta
XP_001101570
619
69877
S166
E
R
M
P
W
Y
H
S
S
L
T
R
E
E
A
Dog
Lupus familis
XP_861301
601
68596
G170
E
K
M
P
W
F
H
G
K
I
S
R
V
E
S
Cat
Felis silvestris
Mouse
Mus musculus
P43404
618
70040
S166
E
R
M
P
W
Y
H
S
S
L
T
R
E
E
A
Rat
Rattus norvegicus
Q64725
629
71510
G170
E
K
M
P
W
F
H
G
N
I
S
R
D
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515271
507
56102
L122
L
R
Q
C
L
R
S
L
G
G
Y
V
L
S
L
Chicken
Gallus gallus
Q07494
984
109166
W378
R
V
F
I
S
S
L
W
A
H
T
P
Y
T
F
Frog
Xenopus laevis
Q91736
902
100832
R300
D
N
V
D
F
V
P
R
Q
L
G
L
T
D
T
Zebra Danio
Brachydanio rerio
O13146
981
109636
V455
E
R
K
G
T
D
S
V
T
L
A
W
Q
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24145
939
104255
S482
K
A
L
F
D
M
N
S
L
R
K
N
K
S
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189062
746
84636
H214
Q
D
K
P
W
F
H
H
K
L
S
R
E
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
53.6
N.A.
93.5
53.7
N.A.
57.6
22.6
24.2
25.2
N.A.
25.1
N.A.
N.A.
34
Protein Similarity:
100
100
98.3
70.4
N.A.
96.1
70.9
N.A.
62.6
35.5
39.1
37.4
N.A.
40.8
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
46.6
N.A.
100
46.6
N.A.
6.6
6.6
6.6
20
N.A.
6.6
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
80
N.A.
100
93.3
N.A.
6.6
13.3
33.3
33.3
N.A.
33.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
9
0
9
0
0
0
42
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
9
9
9
0
0
0
0
0
0
9
9
0
% D
% Glu:
59
0
0
0
0
0
0
0
0
0
0
0
42
59
0
% E
% Phe:
0
0
9
9
9
25
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
9
0
0
0
17
9
9
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
59
9
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
0
% I
% Lys:
9
17
17
0
0
0
0
0
17
0
9
0
9
0
9
% K
% Leu:
9
0
9
0
9
0
9
9
9
59
0
9
9
0
9
% L
% Met:
0
0
50
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
0
9
0
0
9
0
0
0
% N
% Pro:
0
0
0
59
0
0
9
0
0
0
0
9
0
0
9
% P
% Gln:
9
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% Q
% Arg:
9
50
0
0
0
9
0
9
0
9
0
59
0
0
0
% R
% Ser:
0
0
0
0
9
9
17
42
34
0
25
0
0
17
17
% S
% Thr:
0
0
0
0
9
0
0
0
9
0
42
0
9
9
9
% T
% Val:
0
9
9
0
0
9
0
9
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
59
0
0
9
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
34
0
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _